earticle

영어

Acne is an inflammatory skin ailment, one of the common diseases in the sebaceous glands of skin. Propionibacterium acnes (P. acnes), nourished mainly by sebaceous matter, creates free fatty acid by dissolving triglyceride, the main ingredient of sebum. Alginate, richly contained in marine algae such as brown seaweeds and tangle-weeds, faces a rapid increase in demand for a wide utilization as a medical material, finding out its containment of antibacterial materials and unique effects of physiological function. This study has been performed to find out the antibacterial properties of silver alginate (Ag-alginate) and the control groups such as lavender oil, tea tree oil, depolymerized alginate, and silver nanoparticle on P. acnes. Agalginate showed 50 times more effective antibacterial activity than that of control groups in terms of minimum inhibitory concentration (MIC); Ag-alginate of 350 ug/ml, lavender oil 20,000 ug/ml, and depolymerized alginate 10,000 ug/ml. The acne showed improvements in papules and pustules after using the soap and astringent containing 700 ug/ml of Ag-alginate solution. With prolonged use, however, the cosmetics might cause skin stimulus and dryness. Accordingly, it is suggested that effective means of skin care should be implemented together.