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식품 및 바이오신소재

Anticancer Activities of Fractionized Rhodila sachalinensis A. Bor

원문정보

JI HYE HA, JAE GUN HAN, HYANG SUK JEONG, SUNG HO OH, LING JIN, SEUNG SEOP KIM, MYEONG HOON JEONG, HYEON YONG LEE, BAIK HWANG

한국생물공학회 한국생물공학회 학술대회 2009 춘계학술대회 및 국제심포지움 2009.04 pp.153-153
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

1) This study was to compare effects of various solvent fractions of Rhodiola sachalinensis on several kinds of human cancer cell lines. Experimental studies were performed to measure anticancer activities of human cancer cell growth and human immune B and T cell growth. 2) Both human immune B and T cell growth was increased up to 17% adding R. sachalinensis extracts, compared to the control. 3) The cytotoxicity on human kidney cell (HEK293) was showed on lower 4.18% in adding 1.0 mg/mℓ of ethyl acetate fractions. 4) For human stomach adenocarcinoma cells, breast adenocacinoma cells, hepatocellular carcinoma, and lung carcinoma cells, Chloroform fraction extracts inhibited about 60% of cancer cells growth in 1.0 mg/mℓ of the extracts and its selectivity were about 6.5. 5) These results indicate that chloroform fractions of R. sachalinensis have low cytotoxicity on normal cells and high inhibition activity on cancer cell growth. The chloroform fractions could be developed take a of new functional foods material.

키워드

저자정보

  • JI HYE HA Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University,
  • JAE GUN HAN Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University,
  • HYANG SUK JEONG Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University,
  • SUNG HO OH Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University,
  • LING JIN Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University,
  • SEUNG SEOP KIM Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University
  • MYEONG HOON JEONG Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University
  • HYEON YONG LEE Department of Biomaterials Engineering, College of Bioscience and Biotechnology, Kangwon National University
  • BAIK HWANG Department of Biology, Chonnam National University

참고문헌

자료제공 : 네이버학술정보

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