원문정보
초록
영어
Understanding molecular self-assembly of peptides into ordered nanostructures is recently getting much attention from researchers in materials science as well as in chemistry and biology since it can provide an alternative route for fabricating novel bio-inspired materials. Among a number of peptide building blocks reported to date, the simplest building block peptide is diphenylalanine, which constitutes the core-recognition motif of Alzheimer's beta-amyloid peptide and readily assembles into various nanostructures such as nanotubes and organogels. In this presentation, we report the solidphase self-assembly of diphenylalanine peptides into nanostructures, starting from amorphous thin film. We could control the morphology and structures of peptide thin film by inducing the self-assembly of peptide upon exposure to solvent vapor. In particular, we could grow vertically well-aligned peptide nanowires, which are thermally and chemically very stable, by treating the amorphous peptide thin film with aniline vapor at temperatures as high as 100ºC. Lastly, some examples of applications of our peptide nanowire film in nanobiotechnology will be suggested, such as creation of smart surface and templated synthesis of functional nanomaterials.