원문정보
The Principles and Medical Applications of Immunosensors
초록
영어
Immunosensors are of great interest because of their potential utility as specific, simple, label-free, direct detection means and provision of reduction in size, cost and time of analysis comparing with conventional immunoassay. In the last two decades, many reports have been published on the use of immunosensors for a wide range of applications to clinical diagnostics, pharmaceutical chemistry, environmental monitoring, biotechnology and food industries. There are also numerous transduction techniques developed such as electrochemical techniques, piezoelectric crystal, and surface plasmon resonance receiving much attention for the direct monitoring of immune reactions at solid surfaces. In this article, the principles, characteristics, structures, functions and clinical applications of immunosensors were reviewed
목차
서론
변형적 면역분석 측정법(Alternative immunoassay systems)
화학적 면역센서(Electrochemical immunosensor)
전위차 변환기(Potentiometric transducers)
전류 측정 변환기(Amperometric transducers)
전도도 측정 변환기(Conductometric transducers)
임피던스 변환기법(Impedimetric transducers)
면역 컬럼(Immunocolumns): 흐름 주입 면역분석(Flowinjectionimmunoassay)
효소 표지의 전기화학적 검출 면역센서
비효소 표지의 전기화학적 검출 면역센서
직접(비표지) 면역 상호작용을 이용한 전기 화학적 검출 면역센서
질량 검출 면역센서(Mass detecting immunosensors)
압전성 수정결정 면역센서(Piezoelectric quartz crystalimmunosensor)
표면 음파 면역센서(Surface acoustic wave immunosensor,SAW)
광 면역센서(Optical immunosensor)
간접 광 면역센서(Indirect optical immunosensor)
직접 광 센서(Direct optical immunosensor)
형광(Fluorescence)
반사(Reflectance)
Ellipsometry
표면 플라즈몬 공명(Surface plasmon resonance)
도파관(Waveguide)
광 섬유 도파관(Fiber optic waveguides)
간섭기(Interferometers)
회절발 커플러(Grating couplers)
SPR과 간섭원리의 결합
광 칩 면역센서(Optical chip immunosensor)
결론
REFERENCES