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논문검색

Estimation of Stability and Response from Oxygen Mass Transfer Coefficient (kLɑ) in Multi-Fermentor

초록

영어

A Multi-fermentor is an efficient equipment th investigate the effect of operating conditions. In order to exploit the advantage, maintaining the same stable conditions throughout a mult-fermentor is essential except for changing parameter. The oxygen transfer is one of the most important factor in all aerobic fermentations.1,2) Especially, the oxygen mass transfer coefficient (kLɑ) can play a primary role in the scale-up and economical process.3) Since coefficient depends on operational conditions (power input, stirrer speed and gas flow), geometry of the vessel, stirrer, it can serve as a determinate factor on evaluating fermentor performance. In this study, the impact factor of measurement of the kLɑ value were sparger type, impeller size and baffle. In order to obtain the constant value of kLɑ each fermentor has modified sparger
design, impeller size and baffle. The initial average estimated kLɑ values of each six fermentors were 0.032 s-1 with 0.011 standard deviation at 400rpm. The optimal kLɑ average values of each fermentor was 0.030 s-1 and standard deviation was 0.001, which values were obtained by changing sparger and baffle design, position of impeller. The each fermentor also have maintained stable conditions.

저자정보

  • Seok-Young Moon Department of Biological Engineering
  • Sun-ung Heo Department of Biological Engineering
  • Jin-Hyo Yang Department of Biological Engineering
  • Sang-woo Bae Department of Biological Engineering
  • Young-Jun Kim ERC for Advanced Bioseparation Technology Inha University
  • Yoon-Mo Koo Department of Biological Engineering, ERC for Advanced Bioseparation Technology Inha University

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