원문정보
초록
영어
Tetragonia tetragonioides has long been used as a traditional remedy for stomach cancer and furuncle. We investigated antioxidant, acetylcholinesterase (AChE) and lipoxygenase (Lox) activity for the solvent extracts from Tetragonia tetragonioides. The CH2Cl2 and EtOAc extracts of Tetragonia tetragonioides were found to exhibit a distinctive antioxidant activity. The fractions of methanol, n-hexane, CH2Cl2, EtOAc and n-buOH were caused concentration-dependent inhibition of soybean Lox and AChE activity. The results indicate that the fractions of Tetragonia tetragonioides containing these compounds inhibit Lox and AChE activity. The MeOH extracts of
Tetragonia tetragonioides exhibited moderate inhibition of the enzyme, defined as more than 40% at 1 mg/ml. Thus, these compounds or fractions containing them may be beneficial for the treatment of inflammatory conditions and Alzheimer's desease.