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As an extension of existing medical services, the mobile medical platform uses mobile Internet terminals as a carrier to build a real-time, dynamic medical service platform. It shares medical resources with brick-and-mortar hospitals. And it has become a powerful tool for people to obtain and use medical health information and services. However, mobile medical APPs suffer from poor user experience and low user stickiness. Therefore, this study focuses on the factors that affect the user experience of the mobile medical platform, aiming to improve the user experience and enhance the user stickiness of the mobile medical platform. It constructs a theoretical model of the factors influencing the user experience of mobile medical platforms from a health literacy perspective. To test the hypothesized model, we conducted a questionnaire survey of 305 users about the platform usage of the mobile medical platform. At the same time, we empirically tested the constructed model using the research tools AMOS and SPSS. The results of the data analysis showed that most of the hypotheses were supported. Specifically, visual attractiveness has a significant positive effect on user experience; demand satisfaction has a significant positive effect on user experience; health information acquisition ability in the health literacy construct has a positive effect on the user experience through the full mediating effect of demand satisfaction. However, the health information evaluation and utilization ability in the health literacy construct had no significant impact on user experience. This study studied the influencing factors of user experience from the perspective of health literacy. It provides a unique perspective for future research on the user experience of mobile medical platforms and has essential theoretical contributions and practical implications for mobile medical platform operators and designers to improve their services and optimize their design.