@article{ART002829349,
author={Mastroianni Antonio and Greco Sonia and Urso Filippo and Mauro Maria Vittoria and Vangeli Valeria},
title={Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?},
journal={Infection and Chemotherapy},
issn={2093-2340},
year={2022},
volume={54},
number={1},
pages={165-172},
doi={10.3947/ic.2021.0070},
url={https://icjournal.org/DOIx.php?id=10.3947/ic.2021.0070}
}

TY - JOUR
AU - Mastroianni Antonio
AU - Greco Sonia
AU - Urso Filippo
AU - Mauro Maria Vittoria
AU - Vangeli Valeria
TI - Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?
T2 - Infection and Chemotherapy
JO - Infection and Chemotherapy
PY - 2022
VL - 54
IS - 1
PB - 대한감염학회
SP - 165
EP - 172
SN - 2093-2340
AB - This brief report documents the safety and efficacy of high-dose tigecycline as a salvage-therapy in in a case series of five patients with serious central nervous system (CNS) rocky mountain spotted fever (RMSF). These severily ill patients were unable to take any oral drug therapy, parenteral doxycycline was unavailable and absorption of oral doxycycline was a concern in these critically ill patients. As far as we know, we report the successfull use of tigecycline for the treatment of rickettsial meningitis for the first time in Italy. We suggest more studies on tigecycline in severe CNS infections from Rickettsia species and multi-drug resistant bacteria, especially the use of tigecycline at higher than standard doses in these life-threathening infectious diseases.
KW - Tigecycline, Rickettsia, Rickettsiosis, Rickettsia rickettsii, Rocky mountain spotted fever
DO - 10.3947/ic.2021.0070
UR - https://icjournal.org/DOIx.php?id=10.3947/ic.2021.0070
ER -

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria and Vangeli Valeria. 2022, "Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?", Infection and Chemotherapy, vol.54, no.1 pp.165-172. Available from: doi:10.3947/ic.2021.0070

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria, Vangeli Valeria "Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?" Infection and Chemotherapy 54.1 pp.165-172 (2022) : 165.

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria, Vangeli Valeria. Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?. 2022; 54(1), 165-172. Available from: doi:10.3947/ic.2021.0070

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria and Vangeli Valeria. "Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?" Infection and Chemotherapy 54, no.1 (2022) : 165-172.doi: 10.3947/ic.2021.0070

Mastroianni Antonio; Greco Sonia; Urso Filippo; Mauro Maria Vittoria; Vangeli Valeria. Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?. Infection and Chemotherapy, 54(1), 165-172. doi: 10.3947/ic.2021.0070

Mastroianni Antonio; Greco Sonia; Urso Filippo; Mauro Maria Vittoria; Vangeli Valeria. Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?. Infection and Chemotherapy. 2022; 54(1) 165-172. doi: 10.3947/ic.2021.0070

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria, Vangeli Valeria. Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?. 2022; 54(1), 165-172. Available from: doi:10.3947/ic.2021.0070

Mastroianni Antonio, Greco Sonia, Urso Filippo, Mauro Maria Vittoria and Vangeli Valeria. "Does Tigecycline Have a Place in Therapy for Rickettsial Infection of the Central Nervous System?" Infection and Chemotherapy 54, no.1 (2022) : 165-172.doi: 10.3947/ic.2021.0070