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Background/Aims: Endoscopic transpapillary gallbladder drainage (ETPGBD) is gaining popularity for the management of acutecholecystitis (AC) in high-risk patients. However, the stents placed during the procedure are not immune to obstruction. Here wedescribe a novel technique of stenting with two transpapillary stents and evaluate its technical feasibility, safety, and efficacy in AC. Methods: A retrospective analysis of all patients undergoing ETPGBD using dual stents for AC at our institution between November1, 2017 and August 31, 2020 was conducted. We abstracted patient data to evaluate technical and clinical success, adverse events,and long-term outcomes. Two stents were placed either during the index procedure or during an interval procedure performed 4–6weeks after the index procedure. Results: A total of 21 patients underwent ETPGBD with dual stenting (57.14% male, mean age: 62.14±17.21 years). The medianinterval between the placement of the first and the second stents was 37 days (range: 0–226 days). Technical and clinical successrates were 100%, with a recurrence rate of 4.76% (n=1) and adverse event rate of 9.52% (n=2) during a mean follow-up period of471.74±345.64 days (median: 341 days, range: 55–1084 days). Conclusions: ETPGBD with dual gallbladder stenting is a safe and effective technique for long-term gallbladder drainage innon-surgical candidates. Larger controlled studies are needed to validate our findings for the widespread implementation of thistechnique.
