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Radioactive aerosols generated during the decommissioning or decontamination innuclear power plants can be deposited in the body due to workers’ inhalation, and become a majorcontribution in the internal exposure. Therefore, the internal dosimetry is an important procedurefor probably preventing the over-exposure of workers. The bio-kinetic models recommended bythe ICRP are applied to calculate the committed effective dose and bio-assay functions of workers,and used in codes for the internal dosimetry. Organs in the body can be represented as a seriesof mathematical compartments according to the bio-kinetic models (the respiratory tract model,alimentary tract model and systemic model). Recently, the ICRP has issued publications on thenew bio-kinetic models. In this study, we investigated the differences between the previous biokineticmodels and the revised bio-kinetic models of 60Co, which is one of radioactive aerosolsand an important activation product generated during the operation of nuclear power plants. Comparative analysse of the retention fraction and daily excreta fraction of inhaled 60Co aerosolhave shown that the difference between two bio-kinetic models is clear, so the revised bio-kineticmodels must be used in the internal exposure calculation codes.