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This study aimed to investigate awareness, attitudes, and perspectives on precision medicine among health professionals in Koreaand to identify issues that need to be addressed before implementing precision medicine. Mixed methods research was applied. For qualitative research, a semi-structured focus group interview was conducted with six health professionals. For quantitativeresearch, a self-reported survey was administered. A total of 542 health professionals participated in the survey, and 526completed the entire questionnaire. Health professionals showed positive attitudes toward precision medicine. About 95–96% ofrespondents agreed that precision medicine will be effective in treatment and precise diagnosis, and 69.9% reported that theywould participate as study subjects. Meanwhile, they expressed concerns regarding educating patients and health professionals inprecision medicine and developing research and data sharing infrastructure. Also, they emphasized the importance of developingprecision medicine in an equitable way. Despite varying levels of awareness of precision medicine, the health professionals expresseda willingness to engage in precision medicine research, and recommended that health professionals work closely with policymakersto design precision medicine in a way that can be effectively adopted. Health professionals showed had a positive, butcautious, attitude toward precision medicine. The results of this study suggest areas to be addressed before ushering in precisionmedicine in Korea.
