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Background and Objectives:This study aimed to investigate the usefulness of anterior based periosteal (Palva) flap for mastoid cavity obliteration in canal wall down mastoidectomy (CWDM) and review its efficacy in produc- ing a dry, low-maintenance cavity. Materials and Methods:Retrospective study of a consecutive series of proce- dures from 2012 to 2015. 122 consecutive procedures for chronic otitis media or cholesteatoma with a minimum follow-up of 12 months (mean, 21 mo; range, 12-40 months). Results:67 ears of chronic otitis media and 41 ears of cholesteatoma were enrolled to this study, and others were adhesive otitis media (14 ears). 103 ears (84.4%) maintained a small, dry, healthy mastoid cavity. 12 ears (9.8%) had intermittent otorrhea easily controlled by topical treatment, 3 ears (2.5%) had persistent otorrhea. 4 ears (3.3%) had showed reperforation of tympanic membrane. Outcomes remained stable over long follow-up, up to 40 months. Conclusions:Obliteration of mastoid cavity fol- lowing CWDM by an anterior-based periosteal flap is a reliable and effective technique that results in a dry, trouble- free mastoid cavity in 84.4% of patients with active chronic otitis media.