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Purpose: The long-term outcomes of aortic wrapping in patients with ascending aortic aneurysms, which are rare, but can be fatal,remain poorly understood. This retrospective study analyzed the outcomes of aortic diameter, including aortic root, ascending aorta,and proximal arch diameters, after aortic wrapping during aortic valve replacement surgery. Materials and Methods: Ninety-six patients with ascending aortic dilation of 40–55 mm who underwent aortic wrapping duringaortic valve replacement were selected for this study. Aortic diameter was measured at three levels perioperatively and at follow-up(median time of 9.1±4.2 years). A linear mixed-effects model was used to analyze aortic diameter expansion. Results: Freedom from adverse aortic events (aortic dissection or rupture, reoperation, or sudden death) at 10 years was 97.9%. Nosignificant dilation at the level of the sinuses of Valsalva (0.069 mm/year, p=0.524) or ascending aorta (0.152 mm/year, p=0.124) wasobserved. Significant dilation occurred at the proximal aortic arch (0.343 mm/year, p=0.006). Subgroup analysis with a multivariablelinear mixed model identified initial ascending aortic diameter to be a significant predictor of proximal arch dilation (p=0.032). Receiver operating characteristic curve analysis revealed that the cut-off for the prediction of proximal arch redilation was an initialmid-ascending aortic diameter of 47.0 mm (area under the curve 0.747, 90% confidence interval 0.613–0.881, p=0.023). Conclusion: Aortic wrapping could be considered as a safe and long-term therapeutic option. Redilation of the proximal archshould be carefully observed during long-term follow-up.
