초록 열기/닫기 버튼
ObjectiveWe evaluated the clinical characteristics of patients who underwent surgery after high intensity focused ultrasound(HIFU) to treat uterine leiomyoma. MethodsFrom June 2016 to September 2017, patients at our hospital who underwent HIFU to treat uterine leiomyoma priorto surgery were enrolled. All patients underwent pelvic magnetic resonance imaging (MRI) before and after HIFU. If6 months had passed since the last pelvic MRI was performed, imaging was performed again before the operation. ResultsA total of 12 patients were analyzed. The median age was 45 (range, 28–51) years. The median body mass index was24.9 (range, 18.1–29.2) kg/m2. The median size of the leiomyoma was 10.1 (range, 7.8–14.0) cm before HIFU, whichchanged to 8.75 (range, 5.9–14.8) cm after HIFU. The median size increased to 9.1 (range, 5.9–18.0) cm before theoperation. Surgery was planned for several reasons, including an increase in the leiomyoma size (n=6), persistentsymptoms (n=4), and newly developed lesion (n=2). The median interval between HIFU and surgery was 7 (range,3–32) months. Ten of the 12 patients underwent laparoscopic surgery, while the others underwent laparotomy;6 patients also underwent laparoscopic myomectomy, and 4 underwent hysterectomy. Histopathologic findingsshowed infarction-type necrosis surrounded by granulation tissue with the infiltration of lymphocytes andmacrophages in all patients. ConclusionTreatment of leiomyoma with operative procedures should be considered in selected patients with tumor size greaterthan 10 cm, multiple tumors, and persistent symptoms after HIFU treatment.
