초록 열기/닫기 버튼
Background and Objectives This study investigated the relationship between reflux symptomindex (RSI) and psychiatric problems such as depression, somatization, and anxiety. Subjects and Method We prospectively analyzed 231 patients with symptoms with laryngopharyngealreflux (LPR) using the RSI and the reflux finding score. Results Seventy nine patients (34.2%) were diagnosed with LPR. A significant correlationwas detected between the RSI and depression (18.4±8.3 vs. 12.3±7.0, p<0.001), anxiety (19.5±8.5 vs. 13.0±7.3, p<0.001), and somatization (19.2±9.1 vs. 13.6±7.5, p<0.001). A multivariateanalysis confirmed a significant association between heartburn and depression [odds ratio(OR): 1.241, 95% confidence interval (CI): 1.003-1.537, p=0.047], choking and anxiety (OR:1.747, 95% CI: 1.297-2.352, p<0.001), and choking and somatization (OR: 1.707, 95% CI:1.248-2.336, p=0.001). Conclusion Our preliminary results suggest that patients with high RSI may need to becarefully evaluated for psychiatric problems.
