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Headaches are one of the most common conditions associated with temporomandibular disorder (TMD). In the present paper, we evaluated the rela-tionship between headache and TMD, determined whether headache influences the symptoms of TMD, and reported two cases of TMD accompanied by headache. Our practical experience and a review of the literature suggested that headache increases the frequency and intensity of pain parameters, thus complicating dysfunctional diseases in both diagnostic and treatment phases. Therefore, early and multidisciplinary treatment of TMD is neces-sary to avoid the overlap of painful events that could result in pain chronicity.
