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Lipoma rarely occurs in the head and neck region;it is especially rare to find it in the nasal cavity and paranasal sinus probablybecause there are few normal adipose tissue. There has been only one case of septal lipoma reported so far, and here we reportanother case. A 31-year-old female visited our hospital with nasal obstruction. In physical examination, we found 2 cm sizedround mass covered with normal hyperemic mucosa on the right anterior part of nasal septum. On computed tomography, thiswas shown as a low density mass. The mass was completely resected via endonasal approach under general anesthesia. Thehistopathological diagnosis was lipoma. This case was different from the previously reported one in that this one was located atthe anterior septal portion of the septum and had a wide base without stalk. (Korean J Otolaryngol 2006;49:568-70)