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The blood glucose and hemoglobin A1c (HbA1c) tests play important roles in many diabetes research projects, including the Diabetes Control and Complications Trial (DCCT). This study was conducted to research the effectiveness of conducting HbA1c tests with NaF containers that have been used for blood glucose testing in diabetes screening. We performed glucose tests (HA7170, Hexokinase method) and HbA1cs (Variant II, HPLC method) with 150 patient subjects. The correlation coefficients value(r) was 0.9943 (P<0.01, y=0.9967x+0.0275) for HbA1c tests using the EDTA and NaF containers. Compared with glucose concentrations, mean HbA1c concentrations were 70-110 mg/dL 5.21±0.52%, 110-200 mg/dL 5.36±0.88%, and 200-400 mg/dL 9.71±3.22% with the correlation coefficients value(r)=0.6381(P<0.01, y=0.0227x+ 2.9434). These results suggest that performing blood glucose and HbA1c tests with NaF containers at the same time is a possibility. In the abnormal range of blood glucose test levels(110 mg/dL > blood glucose>200 mg/dL), the rate of accordance with HbA1c readings is greater than 95%. In the range of normal blood glucose test levels(110 mg/dL < blood glucose < 200 mg/dL), occurrences where there are high blood glucose readings and normal HbA1c readings is greater than 50%. In general, HbA1c values have been referred to in monitoring MBG (Mean Blood Glucose), but for more precise data, it is important that both tests be conducted together. Furthermore, HbA1c testing is more useful than blood glucose testing because HbA1c determines MBG concentrations that are less affected by time variations than blood glucose test results.
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Glucose, Hemoglobin Alc, Mean blood glucose, NaF
