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Background: Triphasic waves are one of the electroencephalographic patterns that can be usually seen in metabolicencephalopathy. The aim of this study is to compare the clinical and electrophysiologic profiles between patients withand without triphasic waves in metabolic encephalopathy, and reassess the significance of triphasic waves in metabolicencephalopathy. Methods: We recruited 127 patients with metabolic encephalopathy, who were admitted to our hospital. We divided these admitted patients into two groups; those with and without triphasic waves. We analyzed the differenceof duration of hospitalization, mortality rate during admission, Glasgow Coma Scale, severity of electroencephalographicalteration, and presence of acute symptomatic seizures between these two groups. Results: Of the 127 patients withmetabolic encephalopathy, we excluded 67 patients who did not have EEG, and 60 patients finally met the inclusioncriteria for this study. Patients with triphasic waves had more severe electroencephalographic alterations, lower GlasgowComa Scale, and more acute symptomatic seizures than those without triphasic waves. After adjusting the clinicalvariables, Glasgow Coma Scale and acute symptomatic seizures were only significantly different between patients withand without triphasic waves. Conclusions: We demonstrated that patients with triphasic waves in metabolic encephalopathyhad more significant impairment of the brain function. (Korean J Clin Neurophysiol 2014;16:15-20)
