초록 열기/닫기 버튼
Dietary polyphenols has been recognized in recent years as beneficial nutrients in cardiovascular disease prevention, especially for the role against athero-thrombogenesis. Various polyphenols including catechins and resveratrols exhibit an influence on platelet aggregation, which is part of the sequence leading to the formation of thrombus. However, polyphenols from various plant resources with different structures showed inconsistent effect in modulating platelet aggregation. In this review, we investigated the antiplatelet effect of different dietary polyphenols and explored its structure-activity relationship. Various studies related to antiplatelet polyphenols were well discussed with their molecular structure and configuration, thus clarified a comprehensive understanding of the mechanism involved in antithrombotic properties, and provided a theoretical basis for the use of natural ingredients in therapeutic intervention.
