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The purpose of this paper is to show the influence of Early greek medicine on Plato’s Cosmology  Alcmaeon holds that health depends on proportion(equality; isonomia) or proportioned mixture of opposing factors  This notion dominated nearly all greek medicine  and also influenced Plato’s cosmology greatly  Generally early greek doctors believed that man consisted of opposing factors  though these are designated differently  Alcmaeon takes powers - hot and dry  cold and hot  vitter  sweet and the rest as those factors  On the other hand  Philistion of Locri adopts the four element theory of Empedocles  He conceives that human body as a mixture of the four elements  and health consists in proportion of these opposing four element  basically as Alcmaeon  This notion is accepted by Plato  Only Plato differs from Philistion in that he does't consider the four elements as the ultimate factors  In Timaeus Plato explains that the Demiourgos constructed the four elements through introducing 'proportion’ into the primitive materials(the oppositives) by means of shapes and mumbers  And Plato thinks that the cosmic body and soul was constructed basically in the same way as the four elements  This is true of the human body and soul  Also Plato explicates diseases from standpoint of proportion or symmetry  Moreover according to Philebus  the good states(i e  ‘health’  ‘music’  ‘seasons’ etc) in the cosmos arises out of the right mixture of the limit and the unlimited  In other word this mixture is proportioned mixture of the oppositives by aid of ratios  In short Plato believes that both the cosmos itself and the good states is proportioned mixture of the oppositives  Thus Plato’ cosmology is fundamentally based upon Alcmaeon’s or Philistion’s concept of Health