초록 열기/닫기 버튼
Background : Despite an increased incidence of endometrial carcinomas in young Korean women, clinicopathologic characteristics and treatment outcomes have not been analyzed. Methods : We investigated clinicopathologic characteristics of endometrial carcinoma in 48 women who were under the age of 40 in order to determine treatment guideline. Results : According to the criteria of the Korean Society for Obesity, 70.8% of study patients were overweight or obese, with an average body mass index (BMI) of 26.0 kg/㎡. Twelve patients received progesterone treatment only, and 6 of them later had successful pregnancies. The histologic subtype was endometrioid adenocarcinoma in all patients. FIGO stages were 1A (41.7 %), 1B (47.1%), ⅡA (2.8%), ⅡB (2.8%), ⅢA (2.8%), and ⅢC (2.8%). FIGO grades were grade 1 (79%) or 2 (21%). The average depth of invasion, excluding stage 1A, was 4.6 ㎜ in the hysterectomy specimens. Two patients were given post-operative radiation treatment and 4 were treated with chemotherapy. All but one case had an uneventful postoperative course during follow-up. Conclusions : A majority of endometrial carcinomas in young Korean women were associated with an early FIGO stage, favorable histologic subtype and grades, and a good prognosis. Progesterone treatment with close observation was a successful treatment option in a selected group of young patients.
