초록 열기/닫기 버튼
Objective To compare the motor recovery following transverse myelitis in pediatric patients with and without spinal cord atrophy. Method From January 1995 through December 2009, twenty children (8 boys and 12 girls with an onset at 5.7±3.8years) that were diagnosed with transverse myelitis at a Children’s Hospital in Korea, and undertaken an initial and follow-up spine magnetic resonance image (MRI) were included. Medical records and spine MRI scans were reviewed retrospectively. An initial MRI was taken 5.1±8.7 days after the onset. Th e interval between an initial and follow-up MRIs was 33.4±23.0 days. Th e motor recovery diff erences between subjects with and without spinal cord atrophy on follow-up MRIs were determined. Motor recovery was defi ned as the elevation of one or more grades of manual muscle tests of the Medical Research Council. Results Eight patients had developed spinal cord atrophies and 12 patients had not. Of the 8 patients with spinal cord atrophy, 7 showed no motor improvement. Among the 12 patients without atrophy, 11 had motor improvement. Spinal cord atrophy on follow-up MRIs were related to the risk of no motor improvement (odds ratio=77.0, 95% confi dence interval [4.114-1441.049], p-value=0.001). Conclusion Children with transverse myelitis who had developed spinal cord atrophy on follow-up MRIs had poor motor recovery than those who had not. The appearance of spinal cord atrophy on follow-up MRI could be an indicator of poor prognosis in pediatric transverse myelitis.
