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Objective To investigate the effi cacy of ultrasonography (US)-guided injections in patients with low lumbar facet syndrome, compared with that in patients who received fl uoroscopy (FS)-guided injections. Method Fifty-seven subjects with facet syndrome of the lumbar spine of the L4-5 and L5-S1 levels were randomly divided into two groups to receive intraarticular injections into the facet joint. One group received FS-guided facet joint injections and the other group received US-guided facet joint injections. Treatment eff ectiveness was assessed using a visual analogue scale (VAS), physician’s and patient’s global assessment (PhyGA, PaGA), and the modifi ed Oswestry Disability Index (MODI). All parameters were evaluated four times: before injections, and at a week, a month, and three months after injections. We also measured, in both groups, how long it took to complete the whole procedure. Results Each group showed signifi cant improvement from the facet joint injections on the VAS, PhyGA, PaGA,and MODI (p<0.05). However at a week, a month, and three months after injections, no signifi cant diff erences were observed between the groups with regard to VAS, PhyGA, PaGA, and MODI (p>0.05). Statistically signifi cant diff erences in procedure time were observed between groups (FS: 248.7±6.5 sec; US: 263.4±5.9 sec; p=0.023). Conclusion US-guided injections in patients with lumbar facet syndrome are as eff ective as FS-guided injections for pain relief and improving activities of daily living.