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This study conducted regional industry analysis to provide basic data for establishment of counter strategies for Yesan-gun and Hongseong-gun according to transfer of Chungcheongnam-do Provincial Office. It also conducted shift-share analysis and regional growth rate differential analysis using 2007 Gross Regional Domestic Product (GRDP) presented by Chungcheongnam-do in 2010. In this study, shift-share analysis and differential analysis using GRDP have limitations as follows. Regional industries show a more rapid change in their structures with the passage of time, compared with national industries, and a wider range of annual fluctuations. In this regard, small area analysis produces different results depending on the selected point of comparison and shows instability. Moreover, irrespective of diversified classification of industries, it is so difficult to consider their complicated linkage, and to explain all basic factors of regional growth gap. However, among data essential for regional analysis, reliable data are regional input-output tables in the metropolitan self-governing entity level, in addition to inter-regional GRDP alone in the basic self-governing entity level. Accordingly, for more in-depth regional analysis in the basic self-governing entity level, more reliable data should be secured and related research methodologies should be discussed.