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Vancomycin 내성 장알균(vancomycin-resistant enterococci, VRE)은 유럽에서 처음 보고 된 이래로 집락화와 감염율이 지속 적으로 증가되어 전 세계적으로 중요한 병원감염균으로 자리잡고 있다. VRE 확산 방지를 위해 VRE의 전파 기전을 이해 하는 것이 우선이다. 이에 저자는 VRE의 내성 기전, 대륙별 역학 및 최신 분자생물학적 역학 기술을 정리하였다.
Since vancomycin-resistant enterococci (VRE) were first isolated in Europe, rates of VRE colonization and infection have risen steadily. Today VRE have emerged as important nosocomial pathogens worldwide; hence, it is crucial to understand the underlying mechanism in the spreading of VRE. This article reviews the mechanism of resistance to vancomycin and global epidemiology of VRE, as well as the current molecular techniques that are being applied to the epidemiological studies of VRE.
Since vancomycin-resistant enterococci (VRE) were first isolated in Europe, rates of VRE colonization and infection have risen steadily. Today VRE have emerged as important nosocomial pathogens worldwide; hence, it is crucial to understand the underlying mechanism in the spreading of VRE. This article reviews the mechanism of resistance to vancomycin and global epidemiology of VRE, as well as the current molecular techniques that are being applied to the epidemiological studies of VRE.
