초록 열기/닫기 버튼
저자들은 만성 수양성 설사와 전신 쇠약감을 주소로 내원한 75세 남자 환자에서 교원성 대장염으로 진단하였고, 보존적 치료와 로페라미드를 하루 3 mg 투여로 임상 증상의 호전을 보인 증례를 경험하였기에 보고하는 바이다.
Collagenous colitis is recognized as one of the causes of chronic diarrhea accompanied with autoimmune diseases. It is a disease associated with chronic watery diarrhea and typical histologic findings of a thick subepithelial collagenous deposit on biopsy. We experienced a 75-year-old man patient with chronic watery diarrhea and mild abdominal pain for 7 years. Physical examination, laboratory and radiologic studies were unremarkable except hypokalemia. Colonoscopy disclosed mucosal atrophy, loss of submucosal vessel and altered vascularity of terminal ileum, ascending colon. Colonoscopic biopsy revealed homogenous hyaline layered collagen deposition beneath the surface epithelium and Masson's trichrome stain showed collagen deposition. We report the case of collagenous colitis with a review of literature.(Korean J Med 71:75-79, 2006)
