초록 열기/닫기 버튼

식도 칸디다증은 면역결핍상태의 HIV 감염 환자에서 흔하게 관찰될 수 있는 기회감염 중 하나이다. HIV 감염 환자에서 식도 칸디다증의 합병증으로 식도협착증이 발생하는 것은 매우 드문 것으로 알려져 있으며, HIV 감염 환자에서 칸디다 감염으로 인하여 면역재구성염증증후군이 발생하였다는 보고도 없다. 저자들은 면역결핍상태의 HIV 감염 환자에서 심한 식도 칸디다증으로 fluconazole 항진균제 치료와 고강도 항레트로바이러스 치료를 시행한 후 식도 칸디다증은 호전되었지만 반복적인 식도협착증이 발생한 1예를 경험하였기에 보고하는 바이다.


Esophageal candidiasis is a common opportunistic infection that develops in human immunodeficiency virus (HIV)-infected patients. It is usually effectively treated with fluconazole, and the occurrence of an esophageal stricture in association with esophageal candidiasis has rarely been reported in HIV-infected patients. In the case presented here, a 49-year-old man was diagnosed with severe esophageal candidiasis with HIV infection. At the time of the HIV diagnosis, he had immunodeficient status with a CD4+ T lymphocyte count of 150 cells/mm3. He received antifungal treatment with fluconazole and combined antiretroviral therapy. Although the esophageal candidiasis improved with rapid recovery of the CD4+ T lymphocyte count, a recurrent esophageal stricture developed. To treat the recurrent esophageal stricture, the patient received repeated balloon dilatation and stent insertion. We report this rare case of severe esophageal stricture complication of esophageal candidiasis in an HIV-infected patient. (Korean J Med 2012;82:247-251)