초록 열기/닫기 버튼
저자들은 재발성 췌장염과 신장 혈전성 미세혈관병증을 동시에 진단받은 환자에서 LA 양성인 APS를 진단하였고 저용량 스테로이드 및 항응고제로 치료한 증례를 경험하여 문헌고찰과 함께 보고하는 바이다.
Antiphospholipid syndrome (APS) is characterized by vascular thrombosis or recurrent fetal loss in the presence of antiphospholipid antibodies. APS has various manifestations because it can involve any vessel in most organs and tissues. There are a few reports of acute pancreatitis or renal thrombotic microangiopathy accompanying APS, but none on concurrent acute pancreatitis and renal thrombotic microangiopathy in Korea. The clinical consequences can be devastating, so a high index of suspicion is necessary for early diagnosis and treatment. We report an unusual case of APS-associated recurrent pancreatitis and renal thrombotic microangiopathy. A 33-year-old woman was admitted for severe epigastric pain attributed to acute pancreatitis. She subsequently developed an acute kidney injury and the histology revealed thrombotic microangiopathy. Four weeks later, she was readmitted with recurrent pancreatitis. After treatment with anticoagulation and low-dose steroid, her abdominal pain subsided and the amylase and lipase levels normalized.
키워드열기/닫기 버튼
Antiphospholipid syndrome, Pancreatitis, Thrombotic microangiopathy
