초록 열기/닫기 버튼

메티실린내성 황색포도알균(methicillin‐resistant Staphylococcus aureus, MRSA)은 1960년대 처음 보고된 이후 의료 관련 감염의 중요한 원인균으로 잘 알려져 있다[1]. 그런데 최근 10여년 전부터 지역사회관련 MRSA (community-associated MRSA, CA-MRSA)가 출현하기 시작하였고 발생빈도가 세계적으로증가하고 있어 공중보건학적인 면에서 중요한 관심사로 대두되었으며[23], 최근에는 의료기관에서도 CA-MRSA의 분리건수가 점차 증가하는 추세이다[4].


The prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasing worldwide. In Korea, the most common genotype of CA-MRSA is the Panton-Valentine leukocidin-negative, sequence type 72 Staphylococcal cassette chromosome (SCC) mec type IV clone. However, within Korean hospitals, this strain is still not commonly reported. In this study, we describe a case of infective endocarditis caused by Panton-Valentine leukocidin-negative MRSA (ST72-SCCmec type IV A clone). Infection occurred after open reduction and internal fixation due to a right humerus fracture with cerebral hemorrhage. Initially, the patient was treated with linezolid, but with the onset of severe thrombocytopenia, the patient was switched to vancomycin therapy.