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Background: In recent days, the prevalence of childhood metabolic syndrome (MS) has increased substantially due to theincreasing rate of childhood obesity on a global scale. The aims of this study were to detect the important parameters and providethe screening system to prevent cardiovascular disease in adolescents with MS. Methods: Ninety one male adolescents were divided into two groups based on the presence or absence of MS. Anthropometricmeasurement and laboratory study were studied. Intimal medial thickness and pulse wave velocity were estimated. Leftventricular mass index (LVMI), ejection fraction, myocardial velocity, strain and strain rate were measured by tissue Dopplerimaging and strain rate imaging. Results: The prevalence of MS was 7.7%. Weight, body mass index (BMI), waist circumference (WC), glucose, insulin,homeostasis model assessment of insulin resistance, triglyceride and LVMI were significantly increased in the MS group. Highdensity lipoprotein-cholesterol (HDL-C), peak early diastolic myocardial velocity (e’), systolic myocardial velocity (s’) and globallongitudinal strain were significantly lower in the MS group. In univariant analysis, LVMI was significantly correlated with BMI,WC, fat %, fat mass, systolic blood pressure, alanine aminotransferase, total cholesterol (TC) and low density lipoprotein-cholesterol. e’ was significantly correlated with BMI, fat %, fat mass, and HDL-C. Global circumferential strain had significant correlation withglucose and TC. Basal anterolateral strain rate was significantly correlated with weight, BMI, WC, fat %, and fat mass. Conclusion: LVMI, strain and strain rate are practical and accurate parameters for assessment of left ventricular function inadolescents with MS.
