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The purpose of this study is to develop and apply the instruction program for the ‘defense action' chapter in life scienceⅠutilizing student generated role-playing analogy, to examine how the program influence students’ motivation, and to see students’ perception. Research classes were conducted: A teacher explained target concept, students conducted roleplay based on the immunity processes. The students found differences and commonalities between analogies and target conceptes while students discussed generated role-playing analogy and teacher gave the feedback to them. The effectiveness of the instruction program was examined through predicative immunity concept test, science learning motivation test, survey, and interview. Two classes of 10th grade at a high school in Chung-buk were assigned to the control and the treatment group and taught about 'defense action' chapter for 6 class hours. Student generated role-playing analogy instruction was provided to the treatment group (38 students). The traditional instruction was provided to the control group (38 students). The conclusion drawn from this research was as follows: First, the students visualized and understood the abstract immunity concepts and the complex immunity processes through the instruction program. Second, the students were motivated by making analogies and their expectation and goal for their learning were increased through student-generated role-playing analogies. Third, as a result of the survey and interview, it was found that the interest of the students in immunity was increased through student-generated role-playing analogies and the immunity processes were able to be applied into social life. Before the class, they thought the 'defense action' chapter was a difficult lesson to learn, but they changed the perception later. In other words, the instruction program for the ‘defense action' chapter in life scienceⅠ utilizing student generated role-playing analogy can be provided to enhance understanding of abstract concept and was proposed to develop immunity concept class for the first time in Korea.
