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This study investigates the influential relation amongst self-empowerment, academic self-efficacy, learning motivation and outcome of nursing students. And this study analysis the differences in the self-empowerment, academic self-efficacy, learning motivation and outcome by gender. The data was collected from nursing students through a structured questionnaire. The statistical analysis methods were frequency analysis, factor analysis, reliability analysis, t-test, and multiple regression analysis. The self-empowerment of nursing students was classified by the personal capability, self-determination and impact. The academic self-efficacy was classified by the confidence, self-regulation efficacy and task difficulty preference. In addition, the learning motivation was classified by the curiosity, expectation and attention. The self-empowerment of nursing students influenced the academic self-efficacy and learning motivation. Specially, self-determination was important factor for the academic self-efficacy, and impact was important factor for the learning motivation. The self-empowerment and learning motivation of nursing students influenced the learning outcome. Also, the confidence and self-regulation efficacy of the academic self-efficacy influenced the learning outcome. There were significant differences in the self-empowerment, academic self-efficacy, learning motivation and outcome by gender. The results of this study will provide basis data on the self-empowerment program and nursing education to excellent professional human of nursing field.
