@article{ART001085722,
author={Hyun Ju Yoo and Mi Gyeong Jo and Si Jun Park and Yeun Ja Mun and Hyeong Bae Pyo and Kyu Sang Lim and Ki Nam Lee and Won Hong Woo},
title={Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression},
journal={동의생리병리학회지},
issn={1738-7698},
year={2007},
volume={21},
number={4},
pages={998-1003}
}

TY - JOUR
AU - Hyun Ju Yoo
AU - Mi Gyeong Jo
AU - Si Jun Park
AU - Yeun Ja Mun
AU - Hyeong Bae Pyo
AU - Kyu Sang Lim
AU - Ki Nam Lee
AU - Won Hong Woo
TI - Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression
T2 - 동의생리병리학회지
JO - 동의생리병리학회지
PY - 2007
VL - 21
IS - 4
PB - 한의병리학회
SP - 998
EP - 1003
SN - 1738-7698
AB - The green marine algae, Capsosiphon fulvescens (CF) is a food supplement cultivated in south coast of Southern Korea. The purpose of this study was to investigate the mechanism of CF-induced hypopigmentation. The present study was designed to determine the effect of CF extracton melanogenesis in B16 cells, particularly its specific effects on tyrosinase and tyrosinase-related protein 2 (TRP-2). We measured melanin contents and analyzed melanosome associated protein levels using Western blot and Reverse transcription-polymerase chian reaction (RT-PCR) analysis. CF extract markedly inhibited melanin synthesis and tyrosinase activity. In addition, cellular dendricity was slightly decreased by CF extract. In further experiments, CF extract significantly reduced the protein levels of tyrosinase and TRP-2 in B16 cells. RT-PCR analysis revealed that tyrosinase and TRP-2 mRNA levels were unaffected by CF treatment. Therefore, these results suggest that hypopigmentary effect of CF was due to post-translational degradationof tyrosinase and TRP-2.
KW - Capsosiphon fulvescens, hypopigmentation tyrosinase, TRP-2
DO -
UR -
ER -

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee and Won Hong Woo. 2007, "Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression", 동의생리병리학회지, vol.21, no.4 pp.998-1003.

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee, Won Hong Woo "Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression" 동의생리병리학회지 21.4 pp.998-1003 (2007) : 998.

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee, Won Hong Woo. Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression. 2007; 21(4), 998-1003.

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee and Won Hong Woo. "Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression" 동의생리병리학회지 21, no.4 (2007) : 998-1003.

Hyun Ju Yoo; Mi Gyeong Jo; Si Jun Park; Yeun Ja Mun; Hyeong Bae Pyo; Kyu Sang Lim; Ki Nam Lee; Won Hong Woo. Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression. 동의생리병리학회지, 21(4), 998-1003.

Hyun Ju Yoo; Mi Gyeong Jo; Si Jun Park; Yeun Ja Mun; Hyeong Bae Pyo; Kyu Sang Lim; Ki Nam Lee; Won Hong Woo. Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression. 동의생리병리학회지. 2007; 21(4) 998-1003.

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee, Won Hong Woo. Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression. 2007; 21(4), 998-1003.

Hyun Ju Yoo, Mi Gyeong Jo, Si Jun Park, Yeun Ja Mun, Hyeong Bae Pyo, Kyu Sang Lim, Ki Nam Lee and Won Hong Woo. "Capsosiphon Fulvescens Decreases Melanin Synthesis Via Downregulation of Tyrosinase and TRP-2 Expression" 동의생리병리학회지 21, no.4 (2007) : 998-1003.