초록 열기/닫기 버튼


The purpose of this study was to observe the effects of Achyranthes Radix(AR) and electroacupuncture(EA) in rats with rheumatoid arthritis induced by type Ⅱ collagen for 28 days. Control group was daily administered 0.9% NaCl 0.5 ㎖, Group I was daily administered 0.9% NaCl 0.5 ㎖ to arthritic rats, Group Ⅱ was orally administered with Achyranthes Radix 500 ㎎/㎏ 0.5 ㎖ to arthritic rats. Group Ⅲ was given 2 Hz EA of chok samni acupoint(ST36) in the test group for 30 min/days to arthritic rats. Group Ⅳ was daily orally administered with Achyranthes Radix 500 ㎎/㎏ 0.5 ㎖ and 2 Hz EA of chok samni acupoint(ST36) in the test group for 30 min/days to arthritic rats. This studies have been designed to evaluate the hind paw edema, assessment of arthritis indices, analgetic effects by analysis of blood chemistry(WBC, CRP, ALP, AST). In each group, histologic observations, Safranin O-fast green stain were observed and analyzed. The following results were obtained. Group Ⅱ, Ⅲ, Ⅳ were significantly decreased arthritis indices and the rate of paw edema compared with Group Ⅰ. Especially group Ⅳ was the most significantly decreased. The WBC, CRP, AST, ALT was that Group Ⅱ, Ⅲ, Ⅳ were significantly decreased compared with Group Ⅰ. In conclusion, Achyranthes Radix and EA contribute to the improvement of blood chemistry and change in safranin O-fast green by knee joint of arthritic rats.


키워드열기/닫기 버튼

Achyranthes Radix, Electroacupuncture, Rheumatoid arthritis, Safranin O-fast green, blood chemistry