@article{ART001119251,
author={이정기 and 신전수 and 최인홍},
title={Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ},
journal={Yonsei Medical Journal},
issn={0513-5796},
year={2006},
volume={47},
number={3},
pages={354-358}
}

TY - JOUR
AU - 이정기
AU - 신전수
AU - 최인홍
TI - Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ
T2 - Yonsei Medical Journal
JO - Yonsei Medical Journal
PY - 2006
VL - 47
IS - 3
PB - 연세대학교의과대학
SP - 354
EP - 358
SN - 0513-5796
AB - TNF-related apoptosis inducing ligand (TRAIL) expressions were studied in primary human brain astrocytes in response to pro-inflammatory cytokines. When astrocytes were treated with IL-1β, TNF-α or IFN-γ, TRAIL was induced in cultured fetal astrocytes. In particular, IFN-γ induced the highest levels of TRAIL in cultured astrocytes. When astrocytes were pre- reated with IFN-γ, they induced apoptosis in TRAIL-sensitive Peer cells. Our results suggest that IFN-γ modulates the expression of TRAIL in astrocytes, which may enhance cytotoxic sensitivity of infiltrating immune cells or brain cells other than astrocytes during inflammation of brain.
KW - IFN-γ, astrocyte, TRAIL, apoptosis
DO -
UR -
ER -

이정기, 신전수 and 최인홍. 2006, "Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ", Yonsei Medical Journal, vol.47, no.3 pp.354-358.

이정기, 신전수, 최인홍 "Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ" Yonsei Medical Journal 47.3 pp.354-358 (2006) : 354.

이정기, 신전수, 최인홍. Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ. 2006; 47(3), 354-358.

이정기, 신전수 and 최인홍. "Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ" Yonsei Medical Journal 47, no.3 (2006) : 354-358.

이정기; 신전수; 최인홍. Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ. Yonsei Medical Journal, 47(3), 354-358.

이정기; 신전수; 최인홍. Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ. Yonsei Medical Journal. 2006; 47(3) 354-358.

이정기, 신전수, 최인홍. Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ. 2006; 47(3), 354-358.

이정기, 신전수 and 최인홍. "Human Brain Astrocytes Mediate TRAIL-mediated Apoptosis after Treatment with IFN-γ" Yonsei Medical Journal 47, no.3 (2006) : 354-358.