@article{ART001400560,
author={김율리 and 이주영 and 민성길},
title={No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population},
journal={Yonsei Medical Journal},
issn={0513-5796},
year={2010},
volume={51},
number={1},
pages={27-32}
}

TY - JOUR
AU - 김율리
AU - 이주영
AU - 민성길
TI - No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population
T2 - Yonsei Medical Journal
JO - Yonsei Medical Journal
PY - 2010
VL - 51
IS - 1
PB - 연세대학교의과대학
SP - 27
EP - 32
SN - 0513-5796
AB - Purpose: We investigated the association between the tryptohan hydroxylase 1 (TPH1) gene and aggression in schizophrenia in a Korean population. Materials and Methods: The sample included 61 aggressive patients as well as 104 non-aggressive patients from psychiatric hospitals and 335 healthy volunteers in Korea. Blood samples were collected from all participants for TPH1 A218C genotyping. The patients were administered standard psychiatric interviews as well as a self-report questionnaire for anger-related traits. Results: In the case-control phenotypic comparisons, there was no significant association between the aggressive patients and the TPH1 A218C polymorphism. There was no significant effect of the TPH1 genotype on the anger-related traits, or no significant interaction between the genotype and group (aggressive and non-aggressive patients). Conclusion: These findings suggest that TPH1 does not play a major role in aggressive behavior via anger in schizophrenic patients.
KW - Tryptophan hydroxylase, aggression, schizophrenia, anger
DO -
UR -
ER -

김율리, 이주영 and 민성길. 2010, "No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population", Yonsei Medical Journal, vol.51, no.1 pp.27-32.

김율리, 이주영, 민성길 "No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population" Yonsei Medical Journal 51.1 pp.27-32 (2010) : 27.

김율리, 이주영, 민성길. No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population. 2010; 51(1), 27-32.

김율리, 이주영 and 민성길. "No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population" Yonsei Medical Journal 51, no.1 (2010) : 27-32.

김율리; 이주영; 민성길. No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population. Yonsei Medical Journal, 51(1), 27-32.

김율리; 이주영; 민성길. No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population. Yonsei Medical Journal. 2010; 51(1) 27-32.

김율리, 이주영, 민성길. No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population. 2010; 51(1), 27-32.

김율리, 이주영 and 민성길. "No Evidence of an Association between A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene and Aggression in Schizophrenia in a Korean Population" Yonsei Medical Journal 51, no.1 (2010) : 27-32.