@article{ART001143641,
author={Jinyoung Yoo and Ji Han Jung and Seok Jin Kang and Chang Suk Kang},
title={Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma},
journal={Cancer Research and Treatment},
issn={1598-2998},
year={2004},
volume={36},
number={6},
pages={384-388}
}

TY - JOUR
AU - Jinyoung Yoo
AU - Ji Han Jung
AU - Seok Jin Kang
AU - Chang Suk Kang
TI - Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma
T2 - Cancer Research and Treatment
JO - Cancer Research and Treatment
PY - 2004
VL - 36
IS - 6
PB - 대한암학회
SP - 384
EP - 388
SN - 1598-2998
AB - Purpose: 92 kDa matrix metalloproteinase-9 (MMP-9) is believed to play an important role in degrading the matrix and basement membrane, contributing to the invasion and metastasis of malignant solid tumors. However, little is known about its involvement in a malignant fibrous histiocytoma. The aim of this study was to investigate the expression of MMP-9 and to correlate its expression with clinicopathologic parameters in human malignant fibrous histiocytomas. Materials and Methods: Archival tumor tissues from 20 patients with a malignant fibrous histiocytoma were analyzed by immunohistochemistry for the expression of MMP-9. Clinical information was obtained through the computerized retrospective database from the tumor registry. Results: Seventeen of 20 (85%) tumors showed a positive reaction for MMP-9. MMP-9 activity was inversely correlated with patients' survival time (p=.011). There was no significant correlation between the activated MMP-9 expression and all the other clinicopathologic variables. Conclusion: Our data demonstrate that MMP-9 activation is likely to occur in human malignant fibrous histiocytomas. It is also noteworthy that the expression of MMP-9 may aid in predicting patients' poor prognosis.(Cancer Res Treat. 2004;36:384-388)
KW - MMP-9,Malignant histiocytic disorder
DO -
UR -
ER -

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang and Chang Suk Kang. 2004, "Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma", Cancer Research and Treatment, vol.36, no.6 pp.384-388.

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang, Chang Suk Kang "Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma" Cancer Research and Treatment 36.6 pp.384-388 (2004) : 384.

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang, Chang Suk Kang. Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma. 2004; 36(6), 384-388.

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang and Chang Suk Kang. "Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma" Cancer Research and Treatment 36, no.6 (2004) : 384-388.

Jinyoung Yoo; Ji Han Jung; Seok Jin Kang; Chang Suk Kang. Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma. Cancer Research and Treatment, 36(6), 384-388.

Jinyoung Yoo; Ji Han Jung; Seok Jin Kang; Chang Suk Kang. Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma. Cancer Research and Treatment. 2004; 36(6) 384-388.

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang, Chang Suk Kang. Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma. 2004; 36(6), 384-388.

Jinyoung Yoo, Ji Han Jung, Seok Jin Kang and Chang Suk Kang. "Expression of Matrix Metalloproteinase-9 Correlates with Poor Prognosis in Human Malignant Fibrous Histiocytoma" Cancer Research and Treatment 36, no.6 (2004) : 384-388.