도형모사 능력 및 간섭억제 능력에서는 집단간 차이가 유의하지 않았으나 그 외 인지기능들-지능, 언어적 기억, 시각적 기억, 실행기능 중 일부 검사에서는 정신분열병군이 정상인 통제군보다 유의하게 저조한 수행을 나타냈다. 모든 인지 기능에서 살인 정신분열병군과 비살인 정신분열병군 간의 차이는 유의하지 않았다. 공격 행동 과거력, 정신분열병 증상, 성격장애 특성 및 인지 기능 간 상관 분석 이상의 결과에서 살인 정신분열병군과 비살인 정신분열병군 간에 인구학적 변인, 인지기능 측면에서 유의한 차이가 없었으므로 두 집단이 동질한 집단이라는 가정 하에 두 집단 자료의 변인들에 대하여 상관 분석을 실시하였다. 먼저 인지기능과 공격행동 과거력(LHA), 인지기능과 정신분열병 증상평가(PANS) 점수 간의 상관분석을 실시하고 그 결과를 Table 3에 제시하였다. 인지기능에 대한 대표 지수로서, 지능지수, 기억지수, 간섭억제 지표 및 오류억제 지표를 선정하였다. 분석결과, 인지기능 지수와 공격행동의 과거력 간에는 유의한 상관이 없었다. 그러나 PA-NS 총점, 음성증상, 일반증상은 모든 인지기능과 유의한 상관이 있었다. 양성 증상은 지능 및 간섭억제 지표와 유의한 상관이 없었고, 기억 및 오류억제 지표와 유의한 상관이 있었다(Table 3). 다음으로, 인지기능과 반사회적 성격장애 특성, 인지기능과 분열형 성격장애 특성 간의 상관분석을 실시하고 그 결과를 Table 3에 제시하였다. 분석결과, 반사회적 성격장애 특성은 인지기능과 유의한 상관이 없었으나 분열형 성격장애 특성은 인지기능과 유의한 상관이 있었다(Table 3).

Objectives：There is a moderate but significant association between schizophrenia and violence. The purpose of this study is to investigate the relationship between violence and brain cognitive functions in schizophrenic patients who have committed homicide using neuropsychological tests. Methods：The study involved three group of subjects：schizophrenics who have committed homicide (n=51), schizophrenics who have not committed homicide (n=50) and normal control (n=50). Intelligence test (K-WAIS), memory test (Rey-Kim Memory Test) and executive function test (Stroop test, WCST) as well as Positive and Negative Syndrome Scale (PANSS) and Structured Interview for DSM-IV Personality (SIDP) were administered by trained researchers. Results：There were no significant differences in demographic variables among groups. Schizophrenic patients showed overall cognitive deficit in intelligence, memory and executive functions, regardless of homicide behavior. Homicidal schizophrenic group was not significantly different from non-homicidal schizophrenic group in every cognitive domain. There was no significant correlation between index scores of cognitive functions and Life History of Aggression assessment (LHA). However, index scores of cognitive functions were negatively correlated with the PANSS and schizotypal trait scores. Conclusion：Cognitive dysfunction is common across both schizophrenic groups. It doesn’t significantly correlate with homicidal experience, but it correlates with the schizophrenic symptom domains. (J Korean Neuropsychiatr Assoc 2006;45 (2):109-116)

Objectives：There is a moderate but significant association between schizophrenia and violence. The purpose of this study is to investigate the relationship between violence and brain cognitive functions in schizophrenic patients who have committed homicide using neuropsychological tests. Methods：The study involved three group of subjects：schizophrenics who have committed homicide (n=51), schizophrenics who have not committed homicide (n=50) and normal control (n=50). Intelligence test (K-WAIS), memory test (Rey-Kim Memory Test) and executive function test (Stroop test, WCST) as well as Positive and Negative Syndrome Scale (PANSS) and Structured Interview for DSM-IV Personality (SIDP) were administered by trained researchers. Results：There were no significant differences in demographic variables among groups. Schizophrenic patients showed overall cognitive deficit in intelligence, memory and executive functions, regardless of homicide behavior. Homicidal schizophrenic group was not significantly different from non-homicidal schizophrenic group in every cognitive domain. There was no significant correlation between index scores of cognitive functions and Life History of Aggression assessment (LHA). However, index scores of cognitive functions were negatively correlated with the PANSS and schizotypal trait scores. Conclusion：Cognitive dysfunction is common across both schizophrenic groups. It doesn’t significantly correlate with homicidal experience, but it correlates with the schizophrenic symptom domains. (J Korean Neuropsychiatr Assoc 2006;45 (2):109-116)

Homicide· Schizophrenia· Cognitive function.