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Objectives ZZWe investigated the effects of depression on emotional regulation in adolescents with internet gaming disorder. MethodsZZA stroop Match-to-Sample task with emotional interference was applied to 36 male adolescents to investigate how emotional stimuli (angry faces) interfered with performance of the stroop task in male adolescents with internet gaming disorder. For evaluation of psychiatric symptoms and personal characteristics, participants were asked to complete self-reports, including Beck Depression Inventory (BDI), Beck Anxiety Inventory, Barratt Impulsiveness Scale, and the Aggression Questionnaire. ResultsZZIn emotionally interfered conditions, there was no significant difference of reaction time between the internet gaming disorder group and the healthy control group. However, the internet gaming disorder group showed a tendency of longer reaction time and lower accuracy rate in emotionally interfered condition, which can account for emotion regulation difficulties in the internet gaming disorder group. According to analysis of covariance and stepwise multiple linear regression analysis, BDI score showed association with reaction time of results. ConclusionZZThese results indicate that adolescents with internet gaming disorder may experience more difficulties in emotion regulation during attention-required situations than those in the control group, and comorbid depression contributes to faulty emotional regulation in adolescents with internet gaming disorder.