초록 열기/닫기 버튼
Most cases of gas gangrene caused by Clostridium species begin with trauma-related injuries but in rare cases, spontaneousgas gangrene (SGG) can occur when patients have conditions such as advanced malignancy, diabetes, or immunosuppression. Clostridium perfringens, a rare cause of SGG, exists as normal flora of skin and intestines of human. Adequate antibiotics withsurgical debridement of infected tissue is the only curative therapeutic management. Mortality rate among adults is reportedrange of 67-100% and majority of deaths are occurred within 24 hours of onset. We experienced a case of SGG on the trunk,buttock and thigh in a neutropenic patient with acute lymphoblastic leukemia. His clinical course was rapid and fatal duringpre-engraftment neutropenic period of allogeneic stem cell transplantation.
