초록 열기/닫기 버튼

간경변증이 있는 56세 여자가 고열 등의 주소로 내원하였다. 환자는 생선회를 먹었고 입원시에 저혈압을 보였다. 환자의 혈액배양에서V. vulnificus와 V. parahaemolyticus가 동시에 분리되었고, cefotaxime 등이 투여되어 환자는 회복되었다. 혈액에서 2종이상의 Vibrio가 동시에 분리되는 예는 매우 드문데 Vibrio는 균종에 따라서 항균제 감수성과 감염 소견 및 예후가 다르므로 이들을 정확히 분리 동정하는 것은 환자의 치료에 매우 중요하다. 만성 간질환이 있는 환자에서 패혈증이 여름철에 생겼을 때는 혈액에 서 두 가 지Vibrio 균종이 동시에 분리될 수 있음을 Vibrio 감염이 많은 우리나라 미생물 검사자는 염두에 두고 동정에 임해야할 것으로 사료된다.


A 56-year-old woman with underlying liver cirrhosis was hospitalized with chief complaints of fever, which developed after eating raw fish on the previous day. On physical examination, she showed hypotension. Vibrio vulnificus and Vibrio parahaemolyticus strains were simultaneously isolated from blood cultures, and the patient recovered after treatment with antibiotics including cefotaxime. To our knowledge, simultaneous isolation of both V. vulnificus and V. parahaemolyticus from the blood has never been documented before in Korea or any other countries. When blood cultures from a patient with underlying disease such as liver disease show growth of gram-negative bacilli in the summer months, microbiologists in Korea, where Vibrio infection is prevalent, should be aware of the possibility that V. vulnificus and other Vibrio spp. can be isolated simultaneously. An accurate identification of all isolates is important, because antimicrobial susceptibility patterns, severity and prognosis of the infection are different significantly depending on species. (Korean J Lab Med 2004; 24: 173-6)


A 56-year-old woman with underlying liver cirrhosis was hospitalized with chief complaints of fever, which developed after eating raw fish on the previous day. On physical examination, she showed hypotension. Vibrio vulnificus and Vibrio parahaemolyticus strains were simultaneously isolated from blood cultures, and the patient recovered after treatment with antibiotics including cefotaxime. To our knowledge, simultaneous isolation of both V. vulnificus and V. parahaemolyticus from the blood has never been documented before in Korea or any other countries. When blood cultures from a patient with underlying disease such as liver disease show growth of gram-negative bacilli in the summer months, microbiologists in Korea, where Vibrio infection is prevalent, should be aware of the possibility that V. vulnificus and other Vibrio spp. can be isolated simultaneously. An accurate identification of all isolates is important, because antimicrobial susceptibility patterns, severity and prognosis of the infection are different significantly depending on species. (Korean J Lab Med 2004; 24: 173-6)


키워드열기/닫기 버튼

Vibrio vulnificus, Vibrio parahaemolyticus, Simultaneous